The arterial baroreflex and inherent G tolerance

Eur J Appl Physiol. 2016 Jun;116(6):1149-57. doi: 10.1007/s00421-016-3375-1. Epub 2016 Apr 12.

Abstract

Purpose: High G tolerance is based on the capacity to maintain a sufficient level of arterial pressure (AP) during G load; therefore, we hypothesized that subjects with high G tolerance (H group) would have stronger arterial baroreflex responses compared to subjects with low G tolerance (L group). The carotid baroreflex was evaluated using the neck pressure method (NP), which assesses open-loop responses.

Methods: The carotid baroreflex was tested in 16 subjects, n = 8 in the H and L group, respectively, in the supine and upright posture. Heart rate and AP were measured.

Results: There were no differences between groups in the maximum slopes of the carotid baroreflex curves. However, the H group had a larger systolic and mean AP (SAP, MAP) increase to the initial hypotensive stimuli of the NP sequence in the upright position compared to the L group, 7.5 ± 6.6 vs 2.0 ± 2.4 and 4.1 ± 3.4 vs 1.1 ± 1.1 mmHg for SAP and MAP, respectively. Furthermore, the L group exhibited an increased latency between stimuli and response in AP in the upright compared to supine position, 4.1 ± 1.0 vs 3.1 ± 0.9 and 4.7 ± 1.1 vs 3.6 ± 0.9 s, for SAP and MAP. No differences in chronotropic responses were observed between the groups.

Conclusions: It is concluded that the capacity for reflexive vasoconstriction and maintained speed of the vascular baroreflex during orthostatic stress are coupled to a higher relaxed GOR tolerance.

Keywords: Acceleration; Arterial pressure; Baroreflex; G tolerance; Posture.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adaptation, Physiological / physiology*
  • Adult
  • Arterial Pressure / physiology*
  • Baroreflex / physiology*
  • Carotid Sinus / physiology*
  • Humans
  • Hypergravity*
  • Male
  • Orthostatic Intolerance / physiopathology
  • Posture / physiology*