iJGVD: an integrative Japanese genome variation database based on whole-genome sequencing

Yumi Yamaguchi-Kabata; Naoki Nariai; Yosuke Kawai; Yukuto Sato; Kaname Kojima; Minoru Tateno; Fumiki Katsuoka; Jun Yasuda; Masayuki Yamamoto; Masao Nagasaki

doi:10.1038/hgv.2015.50

iJGVD: an integrative Japanese genome variation database based on whole-genome sequencing

Hum Genome Var. 2015 Nov 26:2:15050. doi: 10.1038/hgv.2015.50. eCollection 2015.

Authors

Affiliations

¹ Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan; Graduate School of Medicine, Tohoku University, Sendai, Japan.
² Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University , Sendai, Japan.
³ Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan; Graduate School of Medicine, Tohoku University, Sendai, Japan; Department of Cohort Genome Information Analysis, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
⁴ Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan; Graduate School of Medicine, Tohoku University, Sendai, Japan; Department of Cohort Genome Information Analysis, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan; Graduate School of Information Sciences, Tohoku University, Sendai, Japan.

Abstract

The integrative Japanese Genome Variation Database (iJGVD; http://ijgvd.megabank.tohoku.ac.jp/) provides genomic variation data detected by whole-genome sequencing (WGS) of Japanese individuals. Specifically, the database contains variants detected by WGS of 1,070 individuals who participated in a genome cohort study of the Tohoku Medical Megabank Project. In the first release, iJGVD includes >4,300,000 autosomal single nucleotide variants (SNVs) whose minor allele frequencies are >5.0%.