[Prevalence of atherosclerotic carotid plaques in semi-rural Gueoul, Senegal: Survey of 1411 subjects]

J Mal Vasc. 2016 May;41(3):176-81. doi: 10.1016/j.jmv.2016.03.005. Epub 2016 Apr 15.
[Article in French]

Abstract

Aims: The purpose of this study was to investigate the prevalence of atherosclerotic carotid plaques and association with cardiovascular risk factors and vascular diseases in a semi-rural area of Gueoul in Senegal.

Patients and method: This was a cross-sectional, descriptive study over a period of one month in 2012 in Senegalese people who were older than 35 years, and resided in semi-rural Gueoul for at least six months. Carotid plaques were measured with a portable Doppler Diadop 50(®) and defined by an intima-media thickness greater than 1.5mm. P-values less than 0.05 were considered statistically significant.

Results: The survey involved 1411 individuals with a sex ratio of 2.93 and an average age of 48.5 years. Prevalence of risk factors was high: dyslipidemia (61.1 %), physical inactivity (56.2 %), abdominal obesity (53.9 %), hypertension (46.4 %), obesity (12 %), diabetes (7.2 %) and smoking (2.5 %). Prevalence of atherosclerotic carotid plaques was 6.8 %, including 42.7 % with bilateral plaques. Prevalence increased with age (P=0.001), hypertension (P=0.0001), diabetes (P=0.004) and metabolic syndrome (P=0.008). There were no significant associations with the other risk factors. The presence of carotid plaques was associated with medical history of stroke (P=0.01), myocardial infarction (P=0.02) and peripheral artery obstructive disease (P=0.5).

Conclusion: Prevalence of atherosclerotic carotid plaques seems weak but it is associated with many cardiovascular risk factors. It requires measures for early diagnosis and prevention of cardiovascular diseases in Senegal.

Keywords: Atherosclerotic carotid plaque; Cardiovascular risk factors; Facteurs de risque cardiovasculaires; Gueoul; Guéoul; Intima-media thickness; Plaque d’athérome carotidienne; Senegal; Sénégal; Épaisseur intima-media.

MeSH terms

  • Adult
  • Carotid Artery Diseases / diagnosis
  • Carotid Artery Diseases / epidemiology*
  • Carotid Artery Diseases / prevention & control
  • Cross-Sectional Studies
  • Diabetes Mellitus / epidemiology
  • Dyslipidemias / epidemiology
  • Female
  • Humans
  • Hypertension / epidemiology
  • Male
  • Metabolic Syndrome / epidemiology
  • Middle Aged
  • Obesity / epidemiology
  • Plaque, Atherosclerotic / epidemiology*
  • Risk Factors
  • Rural Population*
  • Senegal / epidemiology
  • Stroke / epidemiology