Liposuction: Extracellular Fat Removal Promotes Proliferation

Robert A Egnatchik; Ralph J DeBerardinis

doi:10.1016/j.chembiol.2016.04.003

Liposuction: Extracellular Fat Removal Promotes Proliferation

Cell Chem Biol. 2016 Apr 21;23(4):431-2. doi: 10.1016/j.chembiol.2016.04.003.

Authors

Robert A Egnatchik¹, Ralph J DeBerardinis²

Affiliations

¹ Children's Medical Center Research Institute at the University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA. Electronic address: [email protected].
² Children's Medical Center Research Institute at the University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA. Electronic address: [email protected].

PMID: 27105278
DOI: 10.1016/j.chembiol.2016.04.003

Abstract

In this issue of Cell Chemical Biology, Yao et al. (2016) investigate the makeup of lipid membranes of both cancer and non-transformed cells to reveal that doubling cells preferentially use exogenous fatty acids over de novo synthesis to proliferate.

MeSH terms

Animals
Cell Proliferation
Fatty Acids / metabolism*
Fibroblasts / cytology
Fibroblasts / metabolism*
Humans
Membrane Lipids / metabolism*
Neoplasms / metabolism*
Neoplasms / pathology

Substances

Fatty Acids
Membrane Lipids