Infections caused by Tissierella praeacuta: A report of two cases and literature review

F Caméléna; B Pilmis; B Mollo; A Hadj; A Le Monnier; A Mizrahi

doi:10.1016/j.anaerobe.2016.04.015

Infections caused by Tissierella praeacuta: A report of two cases and literature review

Anaerobe. 2016 Aug:40:15-7. doi: 10.1016/j.anaerobe.2016.04.015. Epub 2016 Apr 22.

Authors

F Caméléna¹, B Pilmis², B Mollo², A Hadj³, A Le Monnier¹, A Mizrahi⁴

Affiliations

¹ Laboratoire de microbiologie clinique, GH Paris Saint-Joseph, Paris, France.
² Equipe mobile de microbiologie clinique, GH Paris Saint-Joseph, Paris, France.
³ Service de chirurgie orthopédique, GH Paris Saint-Joseph, Paris, France.
⁴ Laboratoire de microbiologie clinique, GH Paris Saint-Joseph, Paris, France. Electronic address: [email protected].

PMID: 27112422
DOI: 10.1016/j.anaerobe.2016.04.015

Abstract

Herein we report two cases of infections caused by Tissierella praeacuta and a review of the literature. The first case was a septic pseudarthrosis of the left femur after multiple fractures. Two per-operative samples were positive with T. praeacuta. The patient was successfully treated by piperacillin - tazobactam and metronidazole. The second case was a bacteremia in a patient suffering from pyonephrosis and a hepatic abscess. The treatment was meropenem. No relapses were observed in both cases. Identification of the strains using MALDI-TOF coupled to mass spectrometry (MS) (Beckman coulter, France) was inconclusive in the two cases. Identification by 16S rRNA sequencing was then performed. This bacterium was susceptible to beta-lactams, chloramphenicol, rifampicine and metronidazole.

Keywords: 16S rRNA; Blood stream infection; Joint infection; MALDI-TOF mass spectrometry; Tissierella praeacuta.

Publication types

Case Reports
Review

MeSH terms

Adult
Aged
Anti-Bacterial Agents / therapeutic use
Bacteremia / complications
Bacteremia / diagnosis*
Bacteremia / drug therapy
Bacteremia / microbiology
Bacterial Typing Techniques
Femoral Neck Fractures / complications
Femoral Neck Fractures / diagnosis*
Femoral Neck Fractures / drug therapy
Femoral Neck Fractures / microbiology
Femur / microbiology
Femur / pathology
Firmicutes / genetics
Firmicutes / isolation & purification*
Humans
Liver Abscess / complications
Liver Abscess / diagnosis*
Liver Abscess / drug therapy
Liver Abscess / microbiology
Meropenem
Penicillanic Acid / analogs & derivatives
Penicillanic Acid / therapeutic use
Piperacillin / therapeutic use
Piperacillin, Tazobactam Drug Combination
Polymerase Chain Reaction
Pseudarthrosis / complications
Pseudarthrosis / diagnosis*
Pseudarthrosis / drug therapy
Pseudarthrosis / microbiology
Pyonephrosis / complications
Pyonephrosis / diagnosis*
Pyonephrosis / drug therapy
Pyonephrosis / microbiology
RNA, Ribosomal, 16S / genetics
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Thienamycins / therapeutic use
Treatment Outcome

Substances

Anti-Bacterial Agents
RNA, Ribosomal, 16S
Thienamycins
Piperacillin, Tazobactam Drug Combination
Penicillanic Acid
Meropenem
Piperacillin