Pilot Randomized Trial of Collaborative Behavioral Treatment for Chronic Pain and Depression in Persons Living with HIV/AIDS

AIDS Behav. 2016 Aug;20(8):1675-81. doi: 10.1007/s10461-016-1397-7.

Abstract

In this pilot study, we assessed feasibility and acceptability of a behavior therapy intervention for pain and depressive symptoms in persons living with HIV/AIDS (PLWH). We randomly assigned 23 participants to HIV-PASS (HIV-Pain and Sadness Study) or a health education control arm for 3 months. On average, participants attended more than 5 sessions (of 7 possible) in both arms. Qualitative data suggest HIV-PASS participants understood key messages and made concrete behavioral changes. HIV-PASS was associated with effects in the expected direction for three of four outcomes, including the primary outcome (pain-related interference with functioning). Findings suggest that HIV-PASS is promising.

Trial registration: ClinicalTrials.gov NCT01735708.

Keywords: Behavioral medicine; Chronic pain; Depression; HIV/AIDS.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications
  • Adult
  • Behavior Therapy / methods*
  • Chronic Pain / psychology
  • Chronic Pain / therapy*
  • Depression / diagnosis
  • Depression / psychology
  • Depression / therapy*
  • Depressive Disorder
  • Female
  • HIV Infections / complications*
  • HIV Infections / psychology
  • Health Education
  • Humans
  • Male
  • Middle Aged
  • Patient Education as Topic / methods
  • Pilot Projects
  • Treatment Outcome

Associated data

  • ClinicalTrials.gov/NCT01735708