Present and future roles of FDG-PET/CT imaging in the management of lung cancer

Kazuhiro Kitajima; Hiroshi Doi; Tomonori Kanda; Tomohiko Yamane; Tetsuya Tsujikawa; Hayato Kaida; Yukihisa Tamaki; Kozo Kuribayashi

doi:10.1007/s11604-016-0546-2

Present and future roles of FDG-PET/CT imaging in the management of lung cancer

Jpn J Radiol. 2016 Jun;34(6):387-99. doi: 10.1007/s11604-016-0546-2. Epub 2016 Apr 27.

Authors

Kazuhiro Kitajima¹, Hiroshi Doi², Tomonori Kanda³, Tomohiko Yamane⁴, Tetsuya Tsujikawa⁵, Hayato Kaida⁶, Yukihisa Tamaki⁷, Kozo Kuribayashi⁸

Affiliations

¹ Division of Nuclear Medicine and PET Center, Department of Radiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan. [email protected].
² Department of Radiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
³ Department of Radiology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605, Japan.
⁴ Department of Nuclear Medicine, Saitama International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
⁵ Department of Biomedical Imaging Research Center, Fukui University, 23-3 Matsuoka-Shimoaizuki, Eiheiji-cho, Fukui, 910-1193, Japan.
⁶ Department of Radiology, Kinki University Faculty of Medicine, 377-2 Ohnohigashi, Osakasayama, Osaka, 589-8511, Japan.
⁷ Department of Radiation Oncology, Shimane University School of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan.
⁸ Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.

PMID: 27121156
DOI: 10.1007/s11604-016-0546-2

Abstract

Integrated positron emission tomography/computed tomography (PET/CT) using 2-[(18)F]fluoro-2-deoxy-D-glucose ((18)F-FDG) has emerged as a powerful tool for combined metabolic and anatomic evaluation in clinical oncologic imaging. This review discusses the utility of (18)F-FDG PET/CT as a tool for managing patients with lung cancer. We discuss different patient management stages, including diagnosis, initial staging, therapy planning, early treatment response assessment, re-staging, and prognosis.

Keywords: Fluorodeoxyglucose (FDG); Lung cancer; Positron emission tomography/computed tomography (PET/CT); Staging; Treatment response assessment.

Publication types

Review

MeSH terms

Fluorodeoxyglucose F18*
Humans
Lung / diagnostic imaging
Lung Neoplasms / diagnostic imaging*
Lung Neoplasms / pathology
Lung Neoplasms / therapy*
Neoplasm Staging
Positron Emission Tomography Computed Tomography*
Radiopharmaceuticals*
Radiotherapy Planning, Computer-Assisted / methods

Substances

Radiopharmaceuticals
Fluorodeoxyglucose F18