Change of hepatic arterial systolic/diastolic ratio predicts ischemic type biliary lesion after orthotropic liver transplantation

Haiming Zhang; Yuexian Shi; Hongtao Wu; Guang Chen; Ying Tang; Lei Liu; Zhijun Zhu

doi:10.1016/j.clinimag.2016.01.013

Change of hepatic arterial systolic/diastolic ratio predicts ischemic type biliary lesion after orthotropic liver transplantation

Clin Imaging. 2016 May-Jun;40(3):419-24. doi: 10.1016/j.clinimag.2016.01.013. Epub 2016 Jan 28.

Authors

Haiming Zhang¹, Yuexian Shi², Hongtao Wu³, Guang Chen⁴, Ying Tang⁵, Lei Liu⁶, Zhijun Zhu⁷

Affiliations

¹ First Central Clinical College of Tianjin Medical University, Tianjin, 300070, China; Tianjin Medical University, Tianjin, 300192, China; Tianjin Key Laboratory of Organ Transplantation, Tianjin, 300192, China. Electronic address: [email protected].
² Tianjin Medical University, Tianjin, 300192, China. Electronic address: [email protected].
³ Tianjin Medical University, Tianjin, 300192, China. Electronic address: [email protected].
⁴ Tianjin Medical University, Tianjin, 300192, China. Electronic address: [email protected].
⁵ Tianjin Medical University, Tianjin, 300192, China. Electronic address: [email protected].
⁶ First Central Clinical College of Tianjin Medical University, Tianjin, 300070, China; Tianjin Medical University, Tianjin, 300192, China; Tianjin Key Laboratory of Organ Transplantation, Tianjin, 300192, China. Electronic address: [email protected].
⁷ First Central Clinical College of Tianjin Medical University, Tianjin, 300070, China; Beijing Friendship Hospital, China Capital Medical University, Beijing, 100050, China. Electronic address: [email protected].

PMID: 27133679
DOI: 10.1016/j.clinimag.2016.01.013

Abstract

Background: We conducted this prospective nested case-control study for the hepatic artery and portal vein hemodynamic changes after orthotopic liver transplantation.

Methods: A total 128 cases of orthotropic liver transplantation were analyzed, including 25 cases of ischemic type biliary lesions (ITBL). The portal vein and hepatic artery flow velocities were detected by ultrasound on days 28, 42, and 84 after liver transplantation. In the GLM analysis of Lg(S/D), the P values of Group Effect, Time Effect, and Time×Group were 0.014, 0.376, and 0.008, respectively.

Conclusion: Our results show a relatively reduced hepatic artery S/D in ITBL, especially in extrahepatic ITBL.

Keywords: Color Doppler flow imaging; Hemodynamics; Hepatic artery; Ischemic type biliary lesions; Liver transplantation.

MeSH terms

Adult
Bile Ducts, Extrahepatic / blood supply
Bile Ducts, Extrahepatic / pathology
Biliary Tract Diseases / blood
Biliary Tract Diseases / diagnostic imaging
Biliary Tract Diseases / etiology*
Blood Flow Velocity
Case-Control Studies
Diagnostic Techniques, Cardiovascular
Diastole*
Female
Hemodynamics
Hepatic Artery / physiopathology*
Humans
Ischemia / complications*
Liver / blood supply*
Liver / pathology
Liver / surgery
Liver Transplantation / adverse effects*
Liver Transplantation / methods
Male
Middle Aged
Portal Vein
Postoperative Complications / diagnostic imaging
Postoperative Complications / etiology
Prospective Studies
Regional Blood Flow
Systole*
Ultrasonography / methods