Abstract
The way in which ketamine exerts its antidepressant effects has been perplexing. Evidence that a metabolite of the drug is responsible, and acts on a different target from ketamine, might be the key to an answer.
MeSH terms
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Animals
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Antidepressive Agents / metabolism*
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Antidepressive Agents / pharmacology*
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Female
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Ketamine / analogs & derivatives*
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Ketamine / metabolism*
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Ketamine / pharmacology
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Male
Substances
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Antidepressive Agents
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Ketamine
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6-hydroxynorketamine