Evaluation of Musculoskeletal Disorders with PET, PET/CT, and PET/MR Imaging

Karen Chen; Judy Blebea; Jean-Denis Laredo; Wengen Chen; Abass Alavi; Drew A Torigian

doi:10.1016/j.cpet.2009.03.003

Evaluation of Musculoskeletal Disorders with PET, PET/CT, and PET/MR Imaging

PET Clin. 2008 Jul;3(3):451-65. doi: 10.1016/j.cpet.2009.03.003. Epub 2009 Jun 21.

Authors

Karen Chen¹, Judy Blebea², Jean-Denis Laredo², Wengen Chen², Abass Alavi², Drew A Torigian²

Affiliations

¹ Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: [email protected].
² Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.

PMID: 27156671
DOI: 10.1016/j.cpet.2009.03.003

Abstract

18F-2-fluoro-2-deoxy-D-glucose-PET has an established role in the evaluation of hip periprosthetic infection and musculoskeletal malignancies. Determination of its role in the management of inflammatory arthritis and diabetic foot complications is ongoing. The reintroduction of fluorine F 18 sodium fluoride as a PET radiotracer may advantageously replace technetium Tc 99 m methylene diphosphonate for some non-oncologic applications, including treatment monitoring of Paget's disease andfibrous dysplasia. The combination of CT or MR imaging with PET imaging synergistically maximizes the diagnostic potential of a combined structural-functional imaging approach for the detection, characterization, and monitoring of myriad musculoskeletal disorders.

Keywords: Arthroplasty; Diabetic foot; Metabolic bone disease; Musculoskeletal; Oncology; PET/CT; PET/MRI; Positron emission tomography (PET).

Published by Elsevier Inc.

Publication types

Review