Application of Advanced MR Imaging Techniques and the Evolving Role of PET/MR Imaging in Neuro-oncology

Thomas C Kwee; Maarten L Donswijk

doi:10.1016/j.cpet.2012.09.003

Application of Advanced MR Imaging Techniques and the Evolving Role of PET/MR Imaging in Neuro-oncology

PET Clin. 2013 Apr;8(2):183-99. doi: 10.1016/j.cpet.2012.09.003. Epub 2012 Nov 24.

Authors

Thomas C Kwee¹, Maarten L Donswijk²

Affiliations

¹ Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands. Electronic address: [email protected].
² Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.

PMID: 27157947
DOI: 10.1016/j.cpet.2012.09.003

Abstract

A requisite to achieve a better outcome in patients with high-grade glioma is the development of noninvasive imaging techniques that improve tumor detection, delineation, and grading, before, during, and after therapy. This article reviews the value of a selection of important advanced MR imaging techniques (diffusion-weighted MR imaging, diffusion-tensor imaging, perfusion MR imaging, and MR spectroscopy) and the evolving role of positron emission tomography (PET)/MR imaging in the evaluation of high-grade gliomas in various settings. This review introduces the reader to the basic principles and clinical applications of these advanced MR imaging and PET/MR imaging techniques.