Screening and Brief Interventions for Illicit Drug Use and Alcohol Use in Methadone Maintained Opiate-Dependent Patients: Results of a Pilot Cluster Randomized Controlled Trial Feasibility Study

Subst Use Misuse. 2016 Jul 28;51(9):1104-15. doi: 10.3109/10826084.2016.1160118. Epub 2016 May 9.

Abstract

Background and objectives: The present study evaluated the effectiveness of a single clinician delivered brief intervention (BI) to reduce problem alcohol use and illicit substance use in an opiate-dependent methadone maintained cohort of patients attending for treatment.

Methods: Four addiction treatment centers were randomly assigned to either treatment as usual (TAU; control group) or BI (intervention group). Clinicians screened patients using the alcohol, smoking, and substance involvement screening test (ASSIST) screening tool at baseline and again at three-month follow up. Fidelity checks were performed to ensure that training was delivered effectively and uniformly across all study sites. Feasibility of administering a BI within daily practice was assessed through intervention fidelity checks, patient satisfaction questionnaires and process evaluation.

Results: A total of 465 patients were screened (66% of the overall eligible population) with a total of 433 (93%) ASSIST positive cases. Randomization was effective, with no differences in the control versus the intervention arms at baseline for key demographic or clinical indicators including substance us. There was a statistically significant difference between global risk score for the intervention (x = 39.36, sd = 25.91) group and the control group (x = 45.27, SD = 27.52) at 3-month follow-up (t(341) = -2.07, p < .05).

Conclusions: This trial provides the first evidence that a single clinician delivered BI can result in a reduction in substance use within a methadone maintained opiate-dependent cohort, and this effect is sustained at three month follow up.

Keywords: Substance abuse; alcohol; illicit drugs; methadone; motivational interviewing; randomized controlled trial.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Alcohol Drinking
  • Feasibility Studies
  • Humans
  • Illicit Drugs
  • Methadone
  • Opiate Alkaloids
  • Pilot Projects
  • Substance-Related Disorders*

Substances

  • Illicit Drugs
  • Opiate Alkaloids
  • Methadone