Herbal medicines with antipyretic action have a long tradition of use in Polish phytotherapy. Over the years, they have proven both their efficacy and safety in a feverishness, which very often have accompanied the upper respiratory tract infections in children. Leading active ingredient of these products is the willow bark (Cortex salicis), which has been the active ingredient in both, the herbal mixture Pyrosan placed on the market in the 50's of last century and Pyrosal syrup marketed in the year 1989. Other herbal substances used in such preparations are elder flower, lime flower and meadowsweet flower. The usage of a pharmaceutical form of syrup is prerequisite when the main group of the patients are children. Such products are continuously in use for nearly 30 years in Poland.