Pseudomembranous colitis secondary to methicillin-resistant Staphylococcus aureus (MRSA)

BMJ Case Rep. 2016 May 10:2016:bcr2016215225. doi: 10.1136/bcr-2016-215225.

Abstract

A 37-year-old woman with a history of type II diabetes and Crohn's disease, status postcholecystectomy, presented with a >2-week history of cramping abdominal pain, nausea, non-bloody/non-bilious emesis and, later, diarrhoea. A flexible sigmoidoscopy was performed, revealing that 'a segmental pseudomembrane was found from rectum to sigmoid colon'. Clostridium difficile PCR on the stool was repeated twice and resulted negative both times. A food history prior to onset of symptoms was consistent with Staphylococcal food poisoning and a stool culture was positive for heavy growth of methicillin-resistant Staphylococcus aureus and the absence of enteric flora. The patient was successfully treated with oral vancomycin.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adult
  • Enterocolitis, Pseudomembranous / drug therapy
  • Enterocolitis, Pseudomembranous / microbiology*
  • Female
  • Humans
  • Methicillin-Resistant Staphylococcus aureus / genetics
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification*
  • Staphylococcal Infections / diagnosis*
  • Staphylococcal Infections / drug therapy
  • Treatment Outcome
  • Vancomycin / administration & dosage*
  • Vancomycin / therapeutic use

Substances

  • Vancomycin