How can we target oxidative stress in the treatment of neurodegenerative diseases?

Future Med Chem. 2016 May;8(8):835-9. doi: 10.4155/fmc-2016-0065. Epub 2016 May 13.

Authors

Hironari Akasaka¹, Ke-He Ruan¹

Affiliation

¹ Department of Pharmacological & Pharmaceutical Sciences, Center for Experimental Therapeutics & PharmacoInformatics, University of Houston College of Pharmacy, Houston, TX 77204-5037, USA.

PMID: 27173453
DOI: 10.4155/fmc-2016-0065

No abstract available

Keywords: lipid oxidation; mitochondria; neurodegenerative diseases; oxidative stress; reactive oxygen species; redox-active metal ions.

Publication types

Editorial

MeSH terms

Antioxidants / chemistry
Antioxidants / pharmacology*
Humans
Mitochondria / drug effects
Mitochondria / metabolism
Neurodegenerative Diseases / drug therapy*
Neurodegenerative Diseases / metabolism
Neurodegenerative Diseases / pathology
Organometallic Compounds / chemistry
Organometallic Compounds / pharmacology*
Oxidative Stress / drug effects*
Oxyquinoline / chemistry
Oxyquinoline / pharmacology*
Reactive Oxygen Species / metabolism

Substances

Antioxidants
Organometallic Compounds
Reactive Oxygen Species
Oxyquinoline