Macrolide antibiotics exert antileukemic effects by modulating the autophagic flux through inhibition of hERG1 potassium channels

Blood Cancer J. 2016 May 13;6(5):e423. doi: 10.1038/bcj.2016.32.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Anti-Bacterial Agents / pharmacology*
  • Antineoplastic Agents / pharmacology*
  • Autophagy / drug effects*
  • ERG1 Potassium Channel / metabolism*
  • Early Detection of Cancer
  • HL-60 Cells
  • Humans
  • Leukemia / metabolism
  • Leukemia / pathology*
  • Macrolides / pharmacology*
  • Signal Transduction / drug effects
  • Tumor Cells, Cultured

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents
  • ERG1 Potassium Channel
  • Macrolides