Taking the RISC of exiting naïve pluripotency

Diana Guallar; Jianlong Wang

doi:10.1186/s13059-016-0979-z

Taking the RISC of exiting naïve pluripotency

Genome Biol. 2016 May 16:17:104. doi: 10.1186/s13059-016-0979-z.

Authors

Diana Guallar^{1

2}, Jianlong Wang^{3

4

5}

Affiliations

¹ The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
² Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
³ The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. [email protected].
⁴ Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. [email protected].
⁵ The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. [email protected].

Abstract

A new study shows how RNA-induced silencing complex (RISC)-mediated posttranscriptional regulation of chromatin remodelers allows for tight control of the naïve-to-primed pluripotency transition.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Argonaute Proteins*
RNA Interference
RNA-Induced Silencing Complex / genetics*

Substances

Argonaute Proteins
RNA-Induced Silencing Complex

Abstract

Publication types

MeSH terms

Substances

Grants and funding