Plasmacytoid dendritic cells (pDCs) and regulatory T (Treg) cells may be the key to viral reactivation in drug-induced hypersensitivity syndrome (DIHS)

Yi-Chun Chen; Michael D Rosenblum; Kanade Shinkai

doi:10.1016/j.jaad.2015.11.031

Plasmacytoid dendritic cells (pDCs) and regulatory T (Treg) cells may be the key to viral reactivation in drug-induced hypersensitivity syndrome (DIHS)

J Am Acad Dermatol. 2016 Jun;74(6):1288-9. doi: 10.1016/j.jaad.2015.11.031.

Authors

Yi-Chun Chen¹, Michael D Rosenblum¹, Kanade Shinkai²

Affiliations

¹ Department of Dermatology, University of California, San Francisco, California.
² Department of Dermatology, University of California, San Francisco, California. Electronic address: [email protected].

PMID: 27185444
DOI: 10.1016/j.jaad.2015.11.031

No abstract available

Keywords: drug reaction with eosinophilia and systemic symptoms; drug-induced hypersensitivity syndrome; plasmacytoid dendritic cells; regulatory T cells; viral reactivation.

Publication types

Editorial

MeSH terms

Dendritic Cells / immunology*
Drug Hypersensitivity Syndrome / immunology*
Herpesviridae / physiology*
Humans
T-Lymphocytes, Regulatory / immunology*
Virus Activation*