Kikuchi-Fujimoto disease: a diagnostic dilemma

Int J Dermatol. 2016 Oct;55(10):1069-75. doi: 10.1111/ijd.13314. Epub 2016 May 21.

Abstract

Kikuchi-Fujimoto disease is a benign, self-limiting condition characterized by lymphadenopathy and fever. Its diagnosis can be challenging, as the disease must be differentiated from lymphoma and systemic lupus erythematosus. Patients can present with nonspecific cutaneous lesions. Adequate clinical and histopathologic correlation can aid in the timely diagnosis of Kikuchi's disease, thus preventing the use of unnecessary diagnostic procedures and inappropriate treatments.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / secondary*
  • Diagnosis, Differential
  • Histiocytic Necrotizing Lymphadenitis / diagnosis*
  • Histiocytic Necrotizing Lymphadenitis / drug therapy
  • Histiocytic Necrotizing Lymphadenitis / pathology*
  • Humans
  • Leukemia, T-Cell / diagnosis*
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lymphatic Metastasis
  • Lymphoma / diagnosis*
  • Prognosis