Heteroarene-Directed Oxidative sp(2) C-H Bond Allylation with Aliphatic Alkenes Catalyzed by an (Electron-Deficient η(5)-Cyclopentadienyl)rhodium(III) Complex

Org Lett. 2016 Jun 17;18(12):2934-7. doi: 10.1021/acs.orglett.6b01288. Epub 2016 May 26.

Abstract

It has been established that the oxidative sp(2) C-H bond allylation with aliphatic alkenes proceeds under mild conditions by using heteroarenes as directing groups and an (electron-deficient η(5)-cyclopentadienyl)rhodium(III) complex, [Cp(E)RhCl2]2, as a precatalyst. In sharp contrast, the use of [Cp*RhCl2]2 instead of [Cp(E)RhCl2]2 led to a complex mixture of products under the same reaction conditions.

Publication types

  • Research Support, Non-U.S. Gov't