Toxoplasmosis, Parvovirus, and Cytomegalovirus in Pregnancy

Deborah M Feldman; Rebecca Keller; Adam F Borgida

doi:10.1016/j.cll.2016.01.011

Toxoplasmosis, Parvovirus, and Cytomegalovirus in Pregnancy

Clin Lab Med. 2016 Jun;36(2):407-19. doi: 10.1016/j.cll.2016.01.011. Epub 2016 Mar 8.

Authors

Deborah M Feldman¹, Rebecca Keller², Adam F Borgida³

Affiliations

¹ Division of Maternal Fetal Medicine, Prenatal Testing Center, Hartford Hospital, University of Connecticut School of Medicine, 85 Jefferson Street, #625, Farmington, CT 06102, USA. Electronic address: [email protected].
² Maternal Fetal Medicine, Obstetrics and Gynecology, UConn Health Center, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA.
³ Division of Maternal Fetal Medicine, Prenatal Testing Center, Hartford Hospital, University of Connecticut School of Medicine, 85 Jefferson Street, #625, Farmington, CT 06102, USA.

PMID: 27235921
DOI: 10.1016/j.cll.2016.01.011

Abstract

There are several infections in adults that warrant special consideration in pregnant women given the potential fetal consequences. Among these are toxoplasmosis, parvovirus B19, and cytomegalovirus. These infections have an important impact on the developing fetus, depending on the timing of infection. This article reviews the modes of transmission as well as maternal and neonatal effects of each of these infections. In addition, the article outlines recommended testing, fetal surveillance, and treatment where indicated.

Keywords: Cytomegalovirus; Diagnosis; Management; Parvovirus; Toxoplasmosis.

Publication types

Review

MeSH terms

Cytomegalovirus Infections / diagnosis*
Female
Humans
Infectious Disease Transmission, Vertical
Parvoviridae Infections / diagnosis*
Pregnancy
Pregnancy Complications, Infectious / diagnosis*
Pregnancy Outcome
Prenatal Diagnosis*
Toxoplasmosis, Congenital / diagnosis*