Dynamic light scattering (DLS)-based immunoassay for ultra-sensitive detection of tumor marker protein

Chem Commun (Camb). 2016 Jun 14;52(50):7850-3. doi: 10.1039/c6cc02633h.

Abstract

A novel dynamic light scattering (DLS)-based immunoassay that utilizes manganese dioxide nanosheet-modified gold nanoparticles (MnO2-GNPs) as an activatable nanoprobe has been developed to detect tumor markers down to femtomolar levels.

MeSH terms

  • Biomarkers, Tumor / analysis*
  • Dynamic Light Scattering*
  • Fluorescent Dyes / chemistry
  • Gold / chemistry*
  • Humans
  • Immunoassay / methods*
  • Manganese Compounds / chemistry*
  • Metal Nanoparticles / chemistry*
  • Molecular Imaging
  • Neoplasm Proteins / analysis*
  • Oxides / chemistry*

Substances

  • Biomarkers, Tumor
  • Fluorescent Dyes
  • Manganese Compounds
  • Neoplasm Proteins
  • Oxides
  • Gold
  • manganese dioxide