Abstract
Phytochemical investigation on the stems of Kadsura renchangiana led to the isolation of two new sesquiterpenoids, renchangianins F and G (1 and 2). Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. The in vitro cytotoxic activities of the isolates were studied against HepG2, A549, and LN229 cancer cell lines.
Keywords:
Kadsura renchangiana; Schisandraceae; cytotoxicity; renchangianin F; renchangianin G; sesquiterpenoids.
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Drug Screening Assays, Antitumor
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Hep G2 Cells
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Humans
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Kadsura / chemistry*
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Plant Stems / chemistry
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
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Sesquiterpenes / pharmacology
Substances
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Antineoplastic Agents, Phytogenic
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Sesquiterpenes
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renchangianin F
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renchangianin G