Obinutuzumab-induced coagulopathy in chronic lymphocytic leukaemia with trisomy 12

Blood Cancer J. 2016 Jun 17;6(6):e435. doi: 10.1038/bcj.2016.42.

Authors

H S Walter¹, S Jayne¹, P Mensah², F M Miall², M Lyttelton³, M J S Dyer¹

Affiliations

¹ Ernest and Helen Scott Haematological Research Institute, University of Leicester, Leicester, UK.
² Department of Haematology, University Hospitals Leicester, Leicester, UK.
³ Department of Haematology, Kettering Hospital NHS Trust, Kettering, UK.

No abstract available

Publication types

Case Reports

MeSH terms

Aged
Antibodies, Monoclonal, Humanized / adverse effects*
Chromosomes, Human, Pair 12*
Disseminated Intravascular Coagulation / chemically induced*
Female
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / complications
Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
Leukemia, Lymphocytic, Chronic, B-Cell / genetics
Leukemia, Lymphocytic, Chronic, B-Cell / pathology
Mutation
Receptor, Notch1 / genetics
Trisomy* / genetics
Trisomy* / pathology

Substances

Antibodies, Monoclonal, Humanized
NOTCH1 protein, human
Receptor, Notch1
obinutuzumab