Autocrine TNF-α and IL-1β prime 6-sulfo LacNAc⁺ dendritic cells for high-level production of IL-23

Exp Dermatol. 2017 Apr;26(4):314-316. doi: 10.1111/exd.13134. Epub 2016 Dec 12.

Authors

Anja Kunze¹, Ulrike Förster¹, Stephanie Oehrl¹, Marc Schmitz², Knut Schäkel¹

Affiliations

¹ Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
² Institute of Immunology, Medical Faculty, Technical University of Dresden, Dresden, Germany.

PMID: 27315572
DOI: 10.1111/exd.13134

No abstract available

Keywords: TNF-α; antibody-mediated treatment; psoriasis; slanDC.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Amino Sugars / metabolism
Autocrine Communication
Dendritic Cells / metabolism*
Humans
Interleukin-23 / metabolism*
Psoriasis / metabolism
Tumor Necrosis Factor-alpha / metabolism

Substances

6-sulfo-LacNac
Amino Sugars
Interleukin-23
Tumor Necrosis Factor-alpha