Molecular interaction of δ-conopeptide EVIA with voltage-gated Na(+) channels

Biochim Biophys Acta. 2016 Sep;1860(9):2053-63. doi: 10.1016/j.bbagen.2016.06.013. Epub 2016 Jun 15.

¹ Eduard-Zintl-Institute of Inorganic and Physical Chemistry, Technische Universität Darmstadt, Alarich-Weiss-Str. 4, D-64287 Darmstadt, Germany.
² Department of Biophysics, Center for Molecular Biomedicine, Friedrich Schiller University Jena and Jena University Hospital, Hans-Knöll-Str. 2, D-07745 Jena, Germany.
³ Pharmaceutical Chemistry I, Pharmaceutical Institute, University of Bonn, Brühler Str. 7, D-53119 Bonn, Germany.
⁴ Clemens-Schöpf-Institute of Organic Chemistry and Biochemistry, Technische Universität Darmstadt, Alarich-Weiss-Str. 4, D-64287 Darmstadt, Germany. Electronic address: [email protected].

No abstract available

Keywords: Conotoxin; Molecular dynamics simulations; NMR structural analysis; Voltage-sensor toxin; δ-EVIA.

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