Molecular Dissection of Complete Response to Receptor Tyrosine Kinase Inhibition in Type II Papillary Renal Cell Carcinoma

Clin Genitourin Cancer. 2017 Feb;15(1):e145-e150. doi: 10.1016/j.clgc.2016.05.019. Epub 2016 May 27.
No abstract available

Keywords: DNA damage repair; Fumarate hydratase; Hereditary leiomyomatosis and renal cell cancer; Pazopanib; Sunitinib.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carcinoma, Renal Cell / drug therapy*
  • Carcinoma, Renal Cell / genetics
  • Exome Sequencing
  • Female
  • Fumarate Hydratase / deficiency
  • GRB2 Adaptor Protein / genetics*
  • Humans
  • Indazoles
  • Indoles / therapeutic use
  • Kidney Neoplasms / drug therapy*
  • Kidney Neoplasms / genetics
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyrimidines / therapeutic use
  • Pyrroles / therapeutic use
  • Sulfonamides / therapeutic use
  • Sunitinib
  • Treatment Outcome
  • Young Adult

Substances

  • GRB2 Adaptor Protein
  • GRB2 protein, human
  • Indazoles
  • Indoles
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Pyrroles
  • Sulfonamides
  • pazopanib
  • Fumarate Hydratase
  • Sunitinib