The Concept of Ecthyma Gangrenosum Illustrated by a Fusarium oxysporum Infection in an Immunocompetent Individual

Yanping Jiang; Abdullah M S Al-Hatmi; Yining Xiang; Yu Cao; Albert H G Gerrits van den Ende; Ilse Curfs-Breuker; Jacques F Meis; Hongguang Lu; G Sybren de Hoog

doi:10.1007/s11046-016-0031-6

The Concept of Ecthyma Gangrenosum Illustrated by a Fusarium oxysporum Infection in an Immunocompetent Individual

Mycopathologia. 2016 Oct;181(9-10):759-63. doi: 10.1007/s11046-016-0031-6. Epub 2016 Jun 21.

Authors

Yanping Jiang^{1

2}, Abdullah M S Al-Hatmi^{3

4

5}, Yining Xiang⁶, Yu Cao¹, Albert H G Gerrits van den Ende¹, Ilse Curfs-Breuker⁷, Jacques F Meis^{7

8}, Hongguang Lu⁹, G Sybren de Hoog^{2

10

11

12}

Affiliations

¹ Department of Dermatology, The Affiliated Hospital, Guizhou Medical University, PO Box 550001, 4 Beijing Road, Guiyang, China.
² CBS-KNAW Fungal Biodiversity Centre, PO Box 85167, 3508 AD, Utrecht, The Netherlands.
³ CBS-KNAW Fungal Biodiversity Centre, PO Box 85167, 3508 AD, Utrecht, The Netherlands. [email protected].
⁴ Institute of Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam, The Netherlands. [email protected].
⁵ Directorate General of Health Services, Ibri Hospital, Ministry of Health, Muscat, Oman. [email protected].
⁶ Departments of Pathology, The Affiliated Hospital, Guizhou Medical University, Guiyang, China.
⁷ Department of Medical Microbiology and Infectious Diseases, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
⁸ Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, The Netherlands.
⁹ Department of Dermatology, The Affiliated Hospital, Guizhou Medical University, PO Box 550001, 4 Beijing Road, Guiyang, China. [email protected].
¹⁰ Institute of Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam, The Netherlands.
¹¹ Basic Pathology Department, Federal University of Paraná State, Curitiba, Paraná, Brazil.
¹² Biology Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Abstract

Ecthyma gangrenosum (EG) involves necrotic cutaneous lesions caused by bacteria, mainly Pseudomonas aeruginosa, and is usually seen in immunocompromised patients with septicemia. However, clinically similar infections have been published with fungi as etiologic agents. We present a case of an EG-like lesion due to Fusarium oxysporum confirmed by clinical diagnosis, culture and molecular identification and discuss the definition of EG.

Keywords: Definition; Ecthyma gangrenosum; Fusarium oxysporum; Immunocompetent.

Publication types

Case Reports

MeSH terms

Adolescent
DNA, Fungal / chemistry
DNA, Fungal / genetics
DNA, Ribosomal Spacer / chemistry
DNA, Ribosomal Spacer / genetics
Ecthyma / etiology*
Ecthyma / pathology*
Fusariosis / diagnosis*
Fusariosis / microbiology
Fusariosis / pathology*
Fusarium / classification
Fusarium / genetics
Fusarium / isolation & purification*
Humans
Male
Microbiological Techniques
Sequence Analysis, DNA

Substances

DNA, Fungal
DNA, Ribosomal Spacer