Repeated fecal microbiota transplantation in a child with ulcerative colitis

Pediatr Int. 2016 Aug;58(8):781-5. doi: 10.1111/ped.12967. Epub 2016 Jun 21.

Abstract

We report the case of an 11-year-old girl with ulcerative colitis refractory to conventional therapy, who was subsequently treated successfully with repeated fecal microbiota transplantation (FMT). The patient was steroid dependent despite several infliximab treatments, and colectomy was proposed to improve quality of life. After repeated FMT, she was able to maintain remission with on minimal dose of steroid. Although her fecal microbiota was dysbiotic before FMT, it was restored to a similar pattern as the donor after repeated FMT.

Keywords: child; fecal microbiota transplantation; inflammatory bowel disease; pediatric; ulcerative colitis.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Colitis, Ulcerative / diagnosis
  • Colitis, Ulcerative / microbiology
  • Colitis, Ulcerative / therapy*
  • Colonoscopy
  • Fecal Microbiota Transplantation / methods*
  • Feces / microbiology
  • Female
  • Humans
  • Remission Induction