CT and MR imaging features of mucinous tubular and spindle cell carcinoma of the kidneys. A multi-institutional review

Eur Radiol. 2017 Mar;27(3):1087-1095. doi: 10.1007/s00330-016-4469-1. Epub 2016 Jun 22.

Abstract

Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney is a recently identified renal malignancy. Diagnosis of this rare subtype of renal tumour can be challenging for pathologists, and as such, any additional data would be helpful to improve diagnostic reliability. As imaging features of this new and rare sub-type have not yet been clearly described, the purpose of this study was to describe the main radiologic features on computed tomography (CT) and magnetic resonance imaging (MRI), based jointly on the literature and findings from a multi-institutional retrospective review of pathology and imaging databases. Using a combination of CT/MRI features, diagnosis of MTSCC could be suggested in many cases. A combination of slow enhancement with plateau on dynamic contrast-enhanced CT/MRI, intermediate to high T2 signal intensity contrasting with low apparent diffusion coefficient values on MRI appeared evocative of this diagnosis.

Key points: • A slow enhancement with plateau is observed either on CT or MRI. • High T2 signal components but low apparent coefficient diffusion are evocative. • T2-weighted imaging features depend on the mucin components of the tumour.

Keywords: Kidney; Magnetic resonance imaging; Mucinous tubular and spindle cell carcinoma of kidney; Renal cell carcinoma; Tumour.

Publication types

  • Multicenter Study

MeSH terms

  • Adenocarcinoma, Mucinous / diagnostic imaging*
  • Adenocarcinoma, Mucinous / pathology
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Kidney Neoplasms / diagnostic imaging*
  • Kidney Neoplasms / pathology
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Mucins
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed*

Substances

  • Mucins