[Trichophyton violaceum : Main cause of tinea capitis in children at Mbarara Regional Referral Hospital in Uganda]

Hautarzt. 2016 Sep;67(9):712-7. doi: 10.1007/s00105-016-3831-1.
[Article in German]

Abstract

Background: Tinea capitis is caused by anthropophilic, zoophilic or geophilic dermatophytes of the genera Microsporum or Trichophyton.

Objective: The aim of this study was to analyze the clinical presentation of tinea capitis among children in western Uganda.

Patients and methods: From February to June 2012, skin and hair samples were obtained from 115 patients aged from 1 to 16 years presenting at Mbarara Regional Referral Hospital (MUSC) with clinically suspected tinea capitis. Conventional mycological diagnostics comprised Blancophor preparation and cultivation of fungi for species identification.

Results: Tinea capitis among the children included in the MUSC study was mainly noninflammatory showing mostly a seborrhoeic pattern or "black dot" and "gray patch" form and highly inflammatory kerion celsi. Blancophor preparation identified 82.6 % positive and 17.4 % negative samples. Cultural species differentiation showed Trichophyton (T.) violaceum as the causative agent for tinea capitis in 56.6 % of the patients. In 13 %, Microsporum (M.) audouinii was isolated followed by T. soudanense (2.6 %), and T. rubrum (1.7 %). In addition, moulds (contamination?) such as Scopulariopsis brevicaulis, Aspergillus niger, and Fusarium oxysporum were found as well as mixed infections.

Conclusion: The anthropophilic dermatophyte T. violaceum represents the most frequent cause of tinea capitis in western Uganda. For successful management oral antifungal therapy is necessary together with supportive topical treatment.

Keywords: Dermatophytes; Fungi; Kerion celsi; Microsporum audouinii; Therapy.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Hospitals, Community / statistics & numerical data
  • Humans
  • Incidence
  • Infant
  • Male
  • Prevalence
  • Referral and Consultation / statistics & numerical data*
  • Risk Factors
  • Species Specificity
  • Tinea / diagnosis*
  • Tinea / epidemiology*
  • Tinea / microbiology
  • Tinea Capitis / diagnosis*
  • Tinea Capitis / epidemiology*
  • Tinea Capitis / microbiology
  • Treatment Outcome
  • Trichophyton / isolation & purification*
  • Uganda / epidemiology

Supplementary concepts

  • Trichophyton infection