Fertility and Early Pregnancy Outcomes Following Conservative Treatment for Cervical Intraepithelial Neoplasia and Early Cervical Cancer

JAMA Oncol. 2016 Nov 1;2(11):1496-1498. doi: 10.1001/jamaoncol.2016.1839.

Abstract

Clinical question: Does local conservative treatment for cervical intraepithelial neoplasia and early invasive cervical cancer adversely affect successful conception and early pregnancy outcomes in the first and second trimester (<24 weeks of gestation)?

Clinical application: Local cervical treatment does not adversely affect fertility or first trimester miscarriage, although it is associated with a significant increase in the risk of second trimester miscarriages.

Publication types

  • Meta-Analysis

MeSH terms

  • Conservative Treatment
  • Female
  • Fertility
  • Fertility Preservation
  • Humans
  • Organ Sparing Treatments
  • Pregnancy
  • Pregnancy Outcome
  • Retrospective Studies
  • Uterine Cervical Dysplasia / therapy*
  • Uterine Cervical Neoplasms / therapy*