The dental surgical management of a patient with a bleeding disorder can present a challenge to the dental provider. This article reviews the clinical presentation of hemophilia and describes the management of 2 patients with hemophilia who presented for dental extractions. Each patient's hematologist was consulted to determine clotting factor replacement therapy, antifibrinolytic therapy, and local measures to obtain hemostasis perioperatively. Careful coordination with the patient's hematologist in such cases is essential to ensure safe treatment.