Case report: successful retreatment of hepatitis C genotype 1b infection with sofosbuvir + simeprevir in a patient with cirrhosis who had prior virologic relapse after treatment with daclatasvir and asunaprevir

Clin Case Rep. 2016 Jun 1;4(7):653-6. doi: 10.1002/ccr3.581. eCollection 2016 Jul.

Abstract

There is currently minimal clinical experience regarding retreatment options for patients failing direct-acting antiviral combination regimens. Here, we report the outcomes of a HCV genotype 1b-infected patient with virologic failure following treatment with daclatasvir and asunaprevir, who was successfully retreated with sofosbuvir plus simeprevir.

Keywords: Asunaprevir; HCV; daclatasvir; retreatment.

Publication types

  • Case Reports