Whole genomic characterization of Korean porcine G8P[7] reassortant rotaviruses

Arch Virol. 2016 Oct;161(10):2835-41. doi: 10.1007/s00705-016-2945-1. Epub 2016 Jul 9.

Abstract

This study analyzed eleven genomic segments of three Korean porcine G8P[7] group A rotavirus (RVA) strains. Phylogenetically, these strains contained two bovine-like and nine porcine-like genomic segments. Eight genes (VP1, VP2, VP6 and NSP1-NSP5) of strains 156-1 and 42-1 and seven genes (VP1, VP2, VP6 and NSP2-NSP5) of strain C-1 clustered closely with porcine and porcine-like animal strains and distantly from typical human Wa-like strains. The VP3-M2 genotype of these strains clustered closely with bovine-like strains, but distantly with typical human DS-1-like strains. These data indicate that multiple reassortments involving porcine and bovine RVA strains in Korea must have occurred.

MeSH terms

  • Animals
  • Cluster Analysis
  • Genome, Viral*
  • Korea
  • Phylogeny
  • RNA, Viral / genetics*
  • Reassortant Viruses / genetics*
  • Reassortant Viruses / isolation & purification
  • Rotavirus / genetics*
  • Rotavirus / isolation & purification
  • Rotavirus Infections / veterinary*
  • Rotavirus Infections / virology
  • Sequence Analysis, DNA*
  • Sequence Homology
  • Swine
  • Swine Diseases / virology*

Substances

  • RNA, Viral