Analyzing CRISPR genome-editing experiments with CRISPResso

Luca Pinello; Matthew C Canver; Megan D Hoban; Stuart H Orkin; Donald B Kohn; Daniel E Bauer; Guo-Cheng Yuan

doi:10.1038/nbt.3583

Analyzing CRISPR genome-editing experiments with CRISPResso

Nat Biotechnol. 2016 Jul 12;34(7):695-7. doi: 10.1038/nbt.3583.

Authors

Luca Pinello^{1

2}, Matthew C Canver^{3

4

5}, Megan D Hoban⁶, Stuart H Orkin^{3

4

5

7}, Donald B Kohn⁶, Daniel E Bauer^{3

4

5}, Guo-Cheng Yuan^{1

2}

Affiliations

¹ Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
² Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
³ Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts, USA.
⁴ Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
⁵ Department of Pediatrics, Harvard Medical School and Harvard Stem Cell Institute, Harvard University, Boston, Massachusetts, USA.
⁶ Department of Microbiology, Immunology, and Molecular Genetics, Eli &Edythe Broad Center of Regenerative Medicine &Stem Cell Research, University of California, Los Angeles, Los Angeles, California, USA.
⁷ Howard Hughes Medical Institute, Boston, Massachusetts, USA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Algorithms
Animals
CRISPR-Cas Systems / genetics*
Clustered Regularly Interspaced Short Palindromic Repeats / genetics*
Computer Simulation
Gene Editing / methods*
High-Throughput Nucleotide Sequencing / methods*
Humans
Models, Genetic*
Sequence Analysis, DNA / methods*
Software*

Publication types

MeSH terms

Grants and funding