Ebola Virus-Related Encephalitis

Clin Infect Dis. 2016 Oct 15;63(8):1076-1078. doi: 10.1093/cid/ciw469. Epub 2016 Jul 14.

Abstract

Ebola patients frequently exhibit behavioral modifications with ideation slowing and aggressiveness, sometimes contrasting with mild severity of Ebola disease. We performed lumbar punctures in 3 patients with this presentation and found Ebola virus in all cerebrospinal fluid samples. This discovery helps to discuss the concept of a specific Ebola virus encephalitis.

Keywords: Ebola virus; behavioral disturbance; encephalitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biomarkers
  • Ebolavirus / genetics*
  • Encephalitis, Viral / cerebrospinal fluid
  • Encephalitis, Viral / diagnosis*
  • Encephalitis, Viral / virology*
  • Female
  • Humans
  • Male
  • Patient Outcome Assessment
  • Phenotype
  • RNA, Viral
  • Real-Time Polymerase Chain Reaction
  • Spinal Puncture
  • Symptom Assessment

Substances

  • Biomarkers
  • RNA, Viral