Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

Andre C Kalil; Mark L Metersky; Michael Klompas; John Muscedere; Daniel A Sweeney; Lucy B Palmer; Lena M Napolitano; Naomi P O'Grady; John G Bartlett; Jordi Carratalà; Ali A El Solh; Santiago Ewig; Paul D Fey; Thomas M File Jr; Marcos I Restrepo; Jason A Roberts; Grant W Waterer; Peggy Cruse; Shandra L Knight; Jan L Brozek

doi:10.1093/cid/ciw353

Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

Clin Infect Dis. 2016 Sep 1;63(5):e61-e111. doi: 10.1093/cid/ciw353. Epub 2016 Jul 14.

Authors

Andre C Kalil¹, Mark L Metersky², Michael Klompas³, John Muscedere⁴, Daniel A Sweeney⁵, Lucy B Palmer⁶, Lena M Napolitano⁷, Naomi P O'Grady⁸, John G Bartlett⁹, Jordi Carratalà¹⁰, Ali A El Solh¹¹, Santiago Ewig¹², Paul D Fey¹³, Thomas M File Jr¹⁴, Marcos I Restrepo¹⁵, Jason A Roberts¹⁶, Grant W Waterer¹⁷, Peggy Cruse¹⁸, Shandra L Knight¹⁸, Jan L Brozek¹⁹

Affiliations

¹ Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha.
² Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington.
³ Brigham and Women's Hospital and Harvard Medical School Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
⁴ Department of Medicine, Critical Care Program, Queens University, Kingston, Ontario, Canada.
⁵ Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego.
⁶ Department of Medicine, Division of Pulmonary Critical Care and Sleep Medicine, State University of New York at Stony Brook.
⁷ Department of Surgery, Division of Trauma, Critical Care and Emergency Surgery, University of Michigan, Ann Arbor.
⁸ Department of Critical Care Medicine, National Institutes of Health, Bethesda.
⁹ Johns Hopkins University School of Medicine, Baltimore, Maryland.
¹⁰ Department of Infectious Diseases, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute, Spanish Network for Research in Infectious Diseases, University of Barcelona, Spain.
¹¹ Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, Veterans Affairs Western New York Healthcare System, New York.
¹² Thoraxzentrum Ruhrgebiet, Department of Respiratory and Infectious Diseases, EVK Herne and Augusta-Kranken-Anstalt Bochum, Germany.
¹³ Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha.
¹⁴ Summa Health System, Akron, Ohio.
¹⁵ Department of Medicine, Division of Pulmonary and Critical Care Medicine, South Texas Veterans Health Care System and University of Texas Health Science Center at San Antonio.
¹⁶ Burns, Trauma and Critical Care Research Centre, The University of Queensland Royal Brisbane and Women's Hospital, Queensland.
¹⁷ School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.
¹⁸ Library and Knowledge Services, National Jewish Health, Denver, Colorado.
¹⁹ Department of Clinical Epidemiology and Biostatistics and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

Abstract

It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances.These guidelines are intended for use by healthcare professionals who care for patients at risk for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), including specialists in infectious diseases, pulmonary diseases, critical care, and surgeons, anesthesiologists, hospitalists, and any clinicians and healthcare providers caring for hospitalized patients with nosocomial pneumonia. The panel's recommendations for the diagnosis and treatment of HAP and VAP are based upon evidence derived from topic-specific systematic literature reviews.

Publication types

Practice Guideline

MeSH terms

Adult
Anti-Bacterial Agents / therapeutic use
Bacteriological Techniques
Cross Infection / diagnosis*
Cross Infection / therapy*
Drug Resistance, Multiple, Bacterial
Humans
Pneumonia, Bacterial / diagnosis*
Pneumonia, Bacterial / therapy*
Pneumonia, Ventilator-Associated / diagnosis*
Pneumonia, Ventilator-Associated / therapy*
United States

Substances

Anti-Bacterial Agents

Grants and funding

K23 HL096054/HL/NHLBI NIH HHS/United States