Uveitis in Chinese Patients with Psoriasis

Ocul Immunol Inflamm. 2017 Dec;25(6):855-865. doi: 10.1080/09273948.2016.1185528. Epub 2016 Jul 15.

Abstract

Purpose: To investigate the clinical features of 51 uveitis patients with psoriasis in China.

Methods: The psoriasis type, demographics, ocular findings, auxiliary examination findings, complications, and therapeutic effects were analyzed.

Results: A total of 37 male and 14 female uveitis patients with psoriasis were classified into four groups: psoriasis vulgaris (29 cases); psoriatic arthritis (15 cases); psoriatic erythroderma (6 cases); and pustular psoriasis (1 case). The onset age of psoriasis was younger than for uveitis (p < 0.001). Anterior uveitis, panuveitis, and posterior uveitis was observed in 58.8%, 35.3%, and 5.9% of the patients, respectively. Hypopyon was more frequently noted in the group with psoriatic arthritis (p = 0.007). Optic disc staining was more frequently noted in the group with psoriatic erythroderma (p = 0.029). Significant visual improvement was observed in 17 patients.

Conclusions: Uveitis can be associated with various types of psoriasis in China, but was most frequently observed in patients with psoriasis vulgaris and psoriatic arthritis.

Keywords: Clinical characteristics; psoriasis; therapeutic effect; uveitis.

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Aged
  • Asian People / ethnology*
  • Child
  • China / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psoriasis / complications*
  • Psoriasis / diagnosis
  • Psoriasis / ethnology
  • Retrospective Studies
  • Tomography, Optical Coherence
  • Uveitis / diagnosis
  • Uveitis / ethnology
  • Uveitis / etiology*
  • Young Adult