Precision treatment with sirolimus in a case of activated phosphoinositide 3-kinase δ syndrome

Affiliations

• ¹ University Hospital Southampton NHS Foundation Trust, Southampton, UK. Electronic address: [email protected].
• ² University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Medicine, University of Southampton, Southampton, UK; Southampton NIHR Wellcome Trust Clinical Research Facility, Southampton, UK.
• ³ Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Cancer Research UK Experimental Cancer Medicine Centre, Southampton, UK.
• ⁴ University Hospital Southampton NHS Foundation Trust, Southampton, UK.
• ⁵ Department of Human Genetics and Genomic Medicine, Faculty of Medicine, University of Southampton, Southampton, UK.
• ⁶ Department of Paediatric Infectious Diseases and Immunology, Southampton Children's Hospital, Southampton, UK.
• ⁷ University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Cancer Research UK Experimental Cancer Medicine Centre, Southampton, UK.