RNA Matchmaking: Finding Cellular Pairing Partners

Mol Cell. 2016 Jul 21;63(2):186-189. doi: 10.1016/j.molcel.2016.07.001.

Abstract

RNA structure is intimately related to function, yet methods to identify base-paired RNA strands in a transcriptome-wide manner in cells have remained elusive. One recent paper in Cell and two in Molecular Cell describe related methods to identify RNA sequences that interact in living cells, setting the stage for breakthroughs in our understanding of RNA structure and function.

Publication types

  • Review

MeSH terms

  • Animals
  • Base Pairing
  • Humans
  • Nucleic Acid Conformation
  • RNA / chemistry*
  • RNA / metabolism
  • Structure-Activity Relationship

Substances

  • RNA