Impaired urine concentrating ability in Itai-itai (ouch-ouch) disease

Int Urol Nephrol. 1989;21(2):201-9. doi: 10.1007/BF02550809.

Abstract

A case of Itai-itai (ouch-ouch) disease with reduced urinary kallikrein excretion and slightly enhanced renin-angiotensin-aldosterone system is described. Although it is well known that cadmium toxicity frequently affects the renal tubular lesions, this report is the first to demonstrate the impaired urine concentrating ability in this disease.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cadmium Poisoning / drug therapy
  • Cadmium Poisoning / physiopathology*
  • Cadmium Poisoning / urine
  • Deamino Arginine Vasopressin / therapeutic use
  • Female
  • Humans
  • Kidney / diagnostic imaging
  • Kidney / physiopathology*
  • Kidney Concentrating Ability*
  • Radionuclide Imaging
  • Renin-Angiotensin System
  • Tomography, X-Ray Computed
  • Urodynamics

Substances

  • Deamino Arginine Vasopressin