First Report of German Cockroaches (Blattella germanica) as Reservoirs of CTX-M-15 Extended-Spectrum-β-Lactamase- and OXA-48 Carbapenemase-Producing Enterobacteriaceae in Batna University Hospital, Algeria

Antimicrob Agents Chemother. 2016 Sep 23;60(10):6377-80. doi: 10.1128/AAC.00871-16. Print 2016 Oct.

Abstract

Here we report the isolation of extended-spectrum β-lactamase (ESBL)- and carbapenemase-producing Enterobacteriaceae from German cockroaches caught in the burn unit of Batna University Hospital in Algeria. Nine of 12 isolates harbored the blaCTX-M-15 ESBL gene. One Enterobacter cloacae isolate belonging to sequence type 528 coexpressed the blaOXA-48, blaCTX-M-15, and blaTEM genes. Our findings indicate that cockroaches may be one of the most dangerous reservoirs for ESBL and carbapenemase producers in hospitals.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algeria
  • Animals
  • Cockroaches / microbiology*
  • Disease Reservoirs
  • Enterobacter cloacae / genetics
  • Enterobacteriaceae / genetics*
  • Enterobacteriaceae / isolation & purification*
  • Hospitals, University
  • beta-Lactamases / genetics*
  • beta-Lactamases / metabolism

Substances

  • beta-lactamase CTX-M-15
  • beta-Lactamases