The Effects of Metabolic Surgery on Fatty Liver Disease and Nonalcoholic Steatohepatitis

Jesse Clanton; Michael Subichin

doi:10.1016/j.suc.2016.03.008

The Effects of Metabolic Surgery on Fatty Liver Disease and Nonalcoholic Steatohepatitis

Surg Clin North Am. 2016 Aug;96(4):703-15. doi: 10.1016/j.suc.2016.03.008.

Authors

Jesse Clanton¹, Michael Subichin²

Affiliations

¹ Department of Surgery, West Virginia University Charleston Division, 3100 MacCorkle Avenue, Medical Staff Office Building, Suite 700, Charleston, WV 25304, USA. Electronic address: [email protected].
² Department of Surgery, Summa Health System, Akron City Hospital, 55 Arch Street, Suite 2F, Akron, OH 44304, USA.

PMID: 27473796
DOI: 10.1016/j.suc.2016.03.008

Abstract

Nonalcoholic fatty liver disease (NAFLD) is an under-recognized but increasingly important manifestation of the metabolic syndrome. Bariatric surgery, both through direct weight loss and more indirect effects on insulin resistance and improvements in inflammatory proteins, can have a profound effect on NAFLD, resulting in improvement or resolution of even high-grade liver disease.

Keywords: Bariatric surgery; Fatty liver disease; NAFLD; NASH.

Publication types

Review

MeSH terms

Bariatric Surgery*
Genetic Predisposition to Disease
Humans
Insulin Resistance
Non-alcoholic Fatty Liver Disease / diagnosis
Non-alcoholic Fatty Liver Disease / genetics
Non-alcoholic Fatty Liver Disease / physiopathology
Non-alcoholic Fatty Liver Disease / surgery*
Treatment Outcome