Objective: A novel technique of placing gold fiducial markers in the breast using ultrasound guidance was developed and performed in 51 of 55 consecutive postlumpectomy patients enrolled in a phase I dose escalation trial of accelerated partial-breast irradiation (APBI) using robotic-based stereotactic body radiation therapy (SBRT).
Conclusion: All 51 postoperative patients underwent successful fiducial placement without complications. Our technique of placing gold fiducial markers in proximity to the seroma cavity is considered safe and effective for breast cancer patients being treated with APBI using robotic-based SBRT.
Keywords: CyberKnife; accelerated partial breast irradiation (APBI); fiducial markers; stereotactic body radiation therapy (SBRT); stereotactic partial-breast irradiation (S-PBI); ultrasound.