Effect of a Dengue Clinical Case Management Course on Physician Practices in Puerto Rico

Clin Infect Dis. 2016 Nov 15;63(10):1297-1303. doi: 10.1093/cid/ciw511. Epub 2016 Aug 8.

Abstract

Background: Prior to 2010, the clinical management of dengue in Puerto Rico was inconsistent with World Health Organization guidelines. A 4-hour classroom-style course on dengue clinical management was developed in 2009 and mandated for Puerto Rico medical licensure in 2010. Fifty physicians were trained as "master trainers" and gave this course to 7638 physicians. This study evaluated the effect of the course on the clinical management of hospitalized dengue patients.

Methods: Pre- and post-course test responses were compared. Changes in physician practices were assessed by reviewing medical records of 430 adult and 1075 pediatric dengue patients at the 12 hospitals in Puerto Rico that reported the most cases during 2008-2009 (pre-intervention) and 2011 (post-intervention). Mixed-effects logistic regression was used to compare key indicators of dengue management.

Results: Physician test scores increased from 48% to 72% correct. Chart reviews showed that the percentage of adult patients who did not receive corticosteroids increased from 30% to 68% (odds ratio [OR], 5.9; 95% confidence interval [CI], 3.7-9.5) and from 91% to 96% in pediatric patients (OR, 2.7; 95% CI, 1.5-4.9). Usage of isotonic intravenous saline during the critical period increased from 57% to 90% in adult patients (OR, 6.2; 95% CI, 1.9-20.4) and from 25% to 44% in pediatric patients (OR, 3.4; 95% CI, 2.2-5.3).

Conclusions: Management of dengue inpatients significantly improved following implementation of a classroom-style course taught by master trainers. An online version of the course was launched in 2014 to expand its reach and sustainability.

Keywords: Puerto Rico; clinical management; dengue; evaluation; key informant interview.

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Inflammatory Agents / therapeutic use
  • Case Management
  • Child
  • Child, Preschool
  • Dengue / epidemiology
  • Dengue / therapy*
  • Education, Medical, Continuing / methods
  • Education, Medical, Continuing / statistics & numerical data*
  • Female
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Infant
  • Infant, Newborn
  • Isotonic Solutions / therapeutic use
  • Male
  • Middle Aged
  • Physicians / statistics & numerical data*
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Puerto Rico
  • Young Adult

Substances

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • Isotonic Solutions