Laboratory testing for the diagnosis, evaluation, and management of systemic lupus erythematosus: Still more questions for the next generations: A Tribute and Thanks and in Memory of my mentor: Henry G. Kunkel

Peter H Schur

doi:10.1016/j.clim.2016.08.006

Laboratory testing for the diagnosis, evaluation, and management of systemic lupus erythematosus: Still more questions for the next generations: A Tribute and Thanks and in Memory of my mentor: Henry G. Kunkel

Clin Immunol. 2016 Nov:172:117-121. doi: 10.1016/j.clim.2016.08.006. Epub 2016 Aug 6.

Author

Peter H Schur¹

Affiliation

¹ Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115, USA.

PMID: 27506962
DOI: 10.1016/j.clim.2016.08.006

Abstract

This paper is a review, personal memoir, a tribute to Henry Kunkel, and a critique regarding laboratory tests used for the evaluation, diagnosis, and understanding Autoimmune Rheumatic Diseases, in particular systemic lupus erythematosus (SLE).

Keywords: ANA; Anti-DNA; Autoantibodies; Complement; Complement genetics; Genetics of SLE.

Publication types

Review

MeSH terms

Autoantibodies / blood
Clinical Laboratory Techniques
Complement System Proteins / deficiency
Complement System Proteins / genetics
Humans
Lupus Erythematosus, Systemic / diagnosis*
Lupus Erythematosus, Systemic / drug therapy
Lupus Erythematosus, Systemic / genetics
Lupus Erythematosus, Systemic / immunology

Substances

Autoantibodies
Complement System Proteins