Solid pseudopapillary neoplasm of the ovary with metastases to the omentum and regional lymph nodes

Indian J Pathol Microbiol. 2016 Jul-Sep;59(3):348-50. doi: 10.4103/0377-4929.188107.

Abstract

Extrapancreatic solid pseudopapillary neoplasms (SPNs) are rare tumors, which bear morphological, immunohistochemical, and molecular features similar to those of pancreatic counterparts. SPN occurs primarily in adolescent girls and young women. It is considered to be a malignant neoplasm with low-grade biology. Ovarian SPNs are uncommon, have benign morphology, usually limited to the ovary and local surgical excision is curative. We report an unusual case of SPN of right ovary with extraovarian spread and metastases to lymph nodes. To the best of our knowledge, this is the second documented case of extragonadal spread of ovarian SPN.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biomarkers, Tumor / analysis
  • CD56 Antigen / analysis
  • Carcinoma, Papillary / diagnosis*
  • Carcinoma, Papillary / pathology
  • Carcinoma, Papillary / secondary*
  • Cyclin D1 / analysis
  • Female
  • Histocytochemistry
  • Humans
  • Immunohistochemistry
  • Lymph Nodes / pathology*
  • Microscopy
  • Neoplasm Metastasis / diagnosis*
  • Neoplasm Metastasis / pathology
  • Neprilysin / analysis
  • Omentum / pathology*
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / secondary*
  • Pelvis / diagnostic imaging
  • Tomography, X-Ray Computed
  • beta Catenin / analysis

Substances

  • Biomarkers, Tumor
  • CD56 Antigen
  • NCAM1 protein, human
  • beta Catenin
  • Cyclin D1
  • Neprilysin