Abstract
Multiple myeloma is a clonal B-cell malignancy, characterised by proliferation of plasma cells and secretion of paraproteins. These plasma cells accumulate predominantly in the bone marrow; rarely, they invade other areas, especially the thorax. Myeloma presenting with a pleural effusion is rare and reported in only 6% of patients with myeloma. Such patients generally present late and have a poor prognosis. Here, we describe a patient presenting with a lung mass, renal failure and a massive unilateral pleural effusion due to multiple myeloma who was treated successfully.
2016 BMJ Publishing Group Ltd.
MeSH terms
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Aged
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bortezomib / administration & dosage
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Dexamethasone / administration & dosage
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Diagnosis, Differential
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Humans
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Kidney Failure, Chronic / complications
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Lenalidomide
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Lung Neoplasms / complications*
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Lung Neoplasms / drug therapy
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Male
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Multiple Myeloma / complications*
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Multiple Myeloma / drug therapy
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Pleural Effusion / diagnostic imaging
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Pleural Effusion / etiology*
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Thalidomide / administration & dosage
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Thalidomide / analogs & derivatives
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Tomography, X-Ray Computed
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Treatment Outcome
Substances
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Thalidomide
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Bortezomib
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Dexamethasone
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Lenalidomide