Differences in physiology related to young or old age and/or organ system impairment alter the absorption, distribution, metabolism, and excretion of many medications and consequently their effectiveness and toxicity. This module discusses common alterations in medication use and dosage that are required in the pediatric age group, in the elderly, and in patients with renal or hepatic disease.
Keywords: drug interactions; entrustable professional activities (EPA) in clinical pharmacology; medical education; medical misadventures; prescribing practices.
© 2016, The American College of Clinical Pharmacology.